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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of cataract
ncRNA name AQP-1 siRNA
ncRNA Category siRNA
Disease name cataract
Species Homo sapiens
Tissues/Cell_line human lens epithelial cell line SRA01/04
Methods siRNA transfection, qRT-PCR, Western blot, CCK-8 assay, flow cytometry
Expression pattern associated
Functional description Decreased cell viability was detected by CCK-8 assay in LECs with siRNA interference, compared to control cells (P<0.05). The apoptosis rate significantly increased in cells after siRNA interference (P<0.05).
PubMed ID 26949604
Year 2016
Title Aquaporin-1 down regulation associated with inhibiting cell viability and inducing apoptosis of human lens epithelial cells.
Drug-related ncRNA NO

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